Modeling Our Molecular World  Summer 2011

"If only molecules could talk... Wait!  They do!"

 Designing HA Binding Proteins

The Model: Jmol Animations
Antibody CR6261 bound to Hemagglutinin
De Novo Protein Attachment to Hemagglutinin
Conserved Locations in Hemagglutinin
Model Description
        •Summary Sheet

"Precipitating" Carbon ... Rubisco

The Model
                   Jmol Animation
Model Descriptions
               •Hexadecamer
               •Dimer

  •Rubisco:  Structure and Function

  •Rubisco Poster

  • Rubisco & Teaching Photosynthesis

"Fixing" Addiction... Cocaine Receptor and Degradation Enzyme

The Models:

The Dopamine (and thus the Cocaine) Receptor (awaiting publishing of the journal article)

Cocaine Degradation Enzyme
        Jmol Animation

 

Some Teaching Tools
Impacts of Drugs on Neurotransmission
• Quiz:  The Brain and Addiction
I Can Quit Anytime I want:  PowerPoint
Case Teaching Notes for "I Can Quit Anytime I Want: The Biological Basis of Euphoria and Addiction”
Mouse Party Worksheet
Drug Abuse and Addiction (includes lesson plans for the Risky Business Card Game) Student Handout
Chemistry of Cocaine 
Bioethics Scenario.. Addiction Vaccination
•Exploring the New Science of Addiction
Treatment Activity and Teacher Guide
Background Information
Possible Cocaine Unit Addiction Plan

Some Videos
How does cocaine affect the brain?
Secret Life of the Brain

Shutting off the "Kill" Switch... XIAP
X-linked inhibitor of apoptosis protein

The Model
                  Jmol Animation
Model Description
        •Summary Sheet

 

 

If you have any questions or concerns, please contact Mr. Heeren at the following email address: bheeren@dce.k12.wi.us

Background images are from pdb files downloaded from the Protein Data Bank.
http://www.rcsb.org/pdb/home/home.do

The images are of catalase, single stranded DNA, and of insulin. 
The pdb file numbers (Brookhaven Extension numbers) are 4BLC, 1EW1,  and 2CEU.